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Barshop Institute for Longevity and Aging Studies

Nicolas Musi, MD

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Nicolas Musi, MD

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Director, Barshop Institute for Longevity and Aging Studies
Director, Center for Healthy Aging
Director, San Antonio Geriatric Research, Education, and Clinical Center (GRECC)
Professor of Medicine
Barshop Institute for Longevity and Aging Studies
South Texas Veterans Health Care System
210-562-6140
RESEARCH INTERESTS:

My research expertise is in aging, insulin resistance and exercise physiology. My research program in metabolic/endocrine gerontology, is devoted to exploring the effects that aging has on numerous metabolic and cellular processes, and relevant to the patho-genesis of age-related diseases such as diabetes, obesity, and sarcopenia. My main clinical interests are (i) pathogenesis, prevention and treatment of diabetes in the elderly; (ii) molecular mechanisms underlying sarcopenia of aging; and (iii) effects of exercise on glucose and lipid metabolism at the whole-body and cellular levels. We conduct our research in human subjects, rodents, and cell cultures.

RECENT PUBLICATIONS:


Hussey SE, Lum H, Alvarez A, Cipriani Y, Garduo-Garcia J, Anaya L, Dube J, Musi N. (2014)  A sustained increase in plasma NEFA upregulates the Toll-like receptor network in human muscle. Diabetologia 2014 Apr;57(3):582-91.

Mariappan MM, Desilva K, Sorice GP, Muscogiuri G, Jimenez F, Ahuja S, Barnes JL, Choudhury GG, Musi N, Defronzo R, Kasinath BS. (2014) Combined acute hyperglycemic and hyperinsulinemic clamp induced profibrotic and proinflammatory responses in the kidney. Am J Physiol Cell Physiol 2014 Feb;306(3):C202-11.

Casiraghi F, Lertwattanarak R, Luzi L, Chavez AO, Davalli AM, Naegelin T, Comuzzie AG, Frost P, Musi N, Folli F. (2013) Energy expenditure evaluation in humans and non-human primates by SenseWear Armband. Validation of energy expenditure evaluation by SenseWear Armband by direct comparison with indirect calorimetry. PLOS one 2013 Sep;19(8).

Defronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Reaven PD, Gastaldelli A. (2013) ACT NOW Study. Prediction of diabetes based on baseline metabolic characteristics in individuals at high risk. Diabetes Care 2013 Sep;36(11):3067-12.

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The Sam and Ann Barshop Institute for Longevity and Aging Studies

15355 Lambda Drive
San Antonio, Texas  78245
P: 210-562-6140 F: 210-562-6110
Contact: barshopinstitute@uthscsa.edu
Updated: 6/22/2011
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