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Barshop Institute for Longevity and Aging Studies

Chih-Ko Yeh, Ph.D., BDS


Chih-Ko Yeh, Ph.D., BDS

Department of Comprehensive Dentistry
University of Texas Health Science Center at San Antonio
Phone: 210-617-5197


Dr. Yeh’s research is focused on studying the effect of aging on oral health, with a special emphasis on saliva and salivary gland biology/physiology. These studies include: 1) monitoring saliva function in clinical samples from aging, hypertensive, and diabetic stratified populations, as well as HIV infected patients, 2) exploring the pathogenesis of age-related oral and salivary gland diseases, and 3) salivary gland regeneration/repair with stem cells using genomic and proteomic approaches. Most recently, his laboratory has been involved in several translational studies developing saliva-based diagnostics for MI and cancer detection using nanotechnology and effective, long-term anti-fungal (specifically, anti-candida) denture materials.  Dr. Yeh’s laboratory contains all necessary equipment and resources for performing modern chemistry, physiology and molecular and cell biology studies.

Selected Publications

Porteous NB, Bizra E, Cothron A, Yeh CK. A survey of infection control teaching in U.S. dental schools. J Dent Educ. 2014 Feb;78(2):187-94.

Diaz de Guillory C, Schoolfield JD, Johnson D, Yeh CK, Chen S, Cappelli DP, Bober-Moken IG, Dang H. Co-Relationships between glandular salivary flow rates and dental caries. Gerodontology. 2013 Jan 4.

Sun X, Cao Z, Yeh CK, Sun Y. Antifungal activity, biofilm-controlling effect, and biocompatibility of poly(N-vinyl-2-pyrrolidinone)-grafted denture materials. Colloids Surf B Biointerfaces. 2013 Oct 1;110:96-104.

Villar CC, Lin AL, Cao Z, Zhao XR, Wu LA, Chen S, Sun Y, Yeh CK. Anticandidal activity and biocompatibility of a rechargeable antifungal denture material. Oral Dis. 2013 Apr;19(3):287-95.

Fu JL, Zhang HM, Zhang H, Kamat A, Yeh CK, Zhang BX. A melatonin-based fluorescence method for the measurement of mitochondrial complex III function in intact cells. J Pineal Res. 2013 Nov;55(4):364-70.


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The Sam and Ann Barshop Institute for Longevity and Aging Studies

15355 Lambda Drive
San Antonio, Texas  78245
P: 210-562-6140 F: 210-562-6150

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