Dr. Yeh’s research is focused on studying the effect of aging on oral health, with a special emphasis on saliva and salivary gland biology/physiology. These studies include: 1) monitoring saliva function in clinical samples from aging, hypertensive, and diabetic stratified populations, as well as HIV infected patients, 2) exploring the pathogenesis of age-related oral and salivary gland diseases, and 3) salivary gland regeneration/repair with stem cells using genomic and proteomic approaches. Most recently, his laboratory has been involved in several translational studies developing saliva-based diagnostics for MI and cancer detection using nanotechnology and effective, long-term anti-fungal (specifically, anti-candida) denture materials. Dr. Yeh’s laboratory contains all necessary equipment and resources for performing modern chemistry, physiology and molecular and cell biology studies.
Porteous NB, Bizra E, Cothron A, Yeh CK. A survey of infection control teaching in U.S. dental schools. J Dent Educ. 2014 Feb;78(2):187-94.
Diaz de Guillory C, Schoolfield JD, Johnson D, Yeh CK, Chen S, Cappelli DP, Bober-Moken IG, Dang H. Co-Relationships between glandular salivary flow rates and dental caries. Gerodontology. 2013 Jan 4.
Sun X, Cao Z, Yeh CK, Sun Y. Antifungal activity, biofilm-controlling effect, and biocompatibility of poly(N-vinyl-2-pyrrolidinone)-grafted denture materials. Colloids Surf B Biointerfaces. 2013 Oct 1;110:96-104.
Villar CC, Lin AL, Cao Z, Zhao XR, Wu LA, Chen S, Sun Y, Yeh CK. Anticandidal activity and biocompatibility of a rechargeable antifungal denture material. Oral Dis. 2013 Apr;19(3):287-95.
Fu JL, Zhang HM, Zhang H, Kamat A, Yeh CK, Zhang BX. A melatonin-based fluorescence method for the measurement of mitochondrial complex III function in intact cells. J Pineal Res. 2013 Nov;55(4):364-70.