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Barshop Institute for Longevity and Aging Studies

Ellen B. Kraig, PhD

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Ellen B. Kraig, PhD

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Professor
Department of Cellular & Structural Biology
University of Texas Health Science Center at San Antonio
Office: 210-567-3818
RESEARCH INTERESTS: It has been well documented that the ability to mount an effective immune response, particularly to a newly encountered antigen, declines significantly with aging. This is reflected in increased susceptibility to infectious diseases and decreased efficacy of vaccines in the elderly. Dr. Kraig's lab uses both murine and non-human primate models to study the effects of aging on the regulation of humoral and cellular immunity with the long-term goal of developing therapeutics to enhance vaccine efficacy in older individuals. However, an increase in immune competence could be accompanied by enhanced pathologies due to augmented inflammation. Thus, the effects of aging and life-extending interventions on immune tolerance are being addressed in a transgenic mouse model of autoimmune myasthenia gravis.

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The Sam and Ann Barshop Institute for Longevity and Aging Studies

15355 Lambda Drive
San Antonio, Texas  78245
P: 210-562-6140 F: 210-562-6110
Contact: barshopinstitute@uthscsa.edu
Updated: 6/22/2011
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