1. Postdoctoral positions are now available from a National Institute on Aging Training Grant to work with one of some 25 participating faculty. Contact Nicolas Musi, MD for information. A list of participating faculty with links to their contact information and individual Web pages may be found in the far right column. For more information regarding application requirements for this postdoctoral fellowship, link here: NIA Biology of Aging Training Grant.
U.S. Citizenship or Permanent Resident Required.
Mitochondrial dysfunction in aging-related metabolic diseases
A postdoctoral scholar position is available immediately at Barshop Aging Institute of University of Texas Health Science Center at San Antonio, a leading institute in aging research, to identify molecular mechanisms that links aging to the onset of aging-related metabolic diseases using molecular, cellular, metabolic, knockout mouse, and lipidomic approaches. The primary focus of the laboratory is on translational aspects of aging and aging-related diseases, including type 2 diabetes, obesity, diabetic complications, and cardiovascular diseases, with an overarching goal to develop novel treatments for these conditions. The laboratory pioneered the initiation identification and functional characterization of PERK kinase and several lipid metabolic enzymes, including the first cardiolipin remodeling enzyme which plays a key role in linking mitochondrial dysfunction to the onset of several aging-related diseases (Cell Metabolism, 12, 154-165; Proc Natl Acad Sci USA, 109(18):6975-80; Mol Cell Biol. 2013 Jul;33(13):2527-34). Required qualifications include a PhD degree in molecular biology, metabolic diseases, or mitochondrial biology with demonstrated productivity in biomedical research. Candidate must be fluent in English. Experience in working with mitochondrial biology and knockout mice are definitely a plus.
Qualified candidate should send a copy of resume and three names of references to Prof. Roger Shi at firstname.lastname@example.org. For more information of the research work of the laboratory, please visit http://www.barshop.uthscsa.edu/main/facultystaff/barshopfaculty/u226.
Dr. Ikeno's laboratory is studying the effects of oxidative stress on aging and age-related pathology, using unique animal models that overexpress or downregulate antioxidant enzymes, including thioredoxin and Cu/Zn SOD. Research projects include: (1) redox sensitive signaling with mice that overexpress thioredoxin 1 or 2; and (2) obesity/inflammation/oxidative damage/insulin signaling with Cu/ZnSOD transgenic rats or mice fed a high-fat diet; (3) anti-tumor actions of caloric restriction.
Experience in standard techniques of molecular and cellular biology is required. A strong research background in the area of oxidative stress and signaling is appreciated.
Please use the link provided to contact Dr. Ikeno for more information.