Metformin for Preventing Frailty in High Risk Older Adults
(This study is now fully enrolled and no additional subjects are currently being recruited)
Frailty Prevention
Purpose of this Study
This project’s overall goal is to determine whether metformin treatment prevents or reduces frailty in older adults who have pre-diabetes.
You may qualify if:
- Age 65 and older
- A non-smoker
- Living independently
Duration of the Study
This is a two-year study with approximately 14 study visits. These visits will occur every 3-6 months.
Study Procedures
- Medical
- Physical examination/assessment
- Blood tests
- Oral Glucose Tolerance Test
- Body composition (DEXA)
- Urine and stool collection
- Muscle specimen (click for more details)
Study Locations
South Texas Veterans Health Care System
Audie L. Murphy Memorial Veterans Hospital
7400 Merton Minter Blvd.
San Antonio, TX 78229
UT Health San Antonio
Sam and Ann Barshop Institute for Longevity and Aging Studies
4939 Charles Katz Dr.
San Antonio, TX 78229
Compensation
Compensation offered for the completion of this study.
Clinical Research Team

Principal Investigator:
Sara Espinoza, MD, MSc
