Strategy for Quantitative Analysis of Isomeric Bis(monoacylglycero)phosphate and Phosphatidylglycerol Species by Shotgun Lipidomics after One-Step Methylation.

October 18, 2019

Strategy for Quantitative Analysis of Isomeric Bis(monoacylglycero)phosphate and Phosphatidylglycerol Species by Shotgun Lipidomics after One-Step Methylation. Wang M, Palavicini JP, Cseresznye A, Han X Analytical Chemistry. 2017 Aug 15;89(16):8490-8495. doi: 10.1021/acs.analchem.7b02058. Epub 2017 Jul 26. Abstract: Understanding the cellular function and metabolism of bis(monoacylglycero)phosphate (BMP), an important but low-abundance class of phospholipids, has been hindered […]


Enhanced coverage of lipid analysis and imaging by matrix-assisted laser desorption/ionization mass spectrometry via a strategy with an optimized mixture of matrices.

October 18, 2019

Enhanced coverage of lipid analysis and imaging by matrix-assisted laser desorption/ionization mass spectrometry via a strategy with an optimized mixture of matrices. Wang J, Wang C, Han X Analytica Chimica Acta. 2018 Feb 13;1000:155-162. doi: 10.1016/j.aca.2017.09.046. Epub 2017 Oct 17. Abstract: In matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) analysis and imaging of lipids, comprehensive […]


Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome.

October 18, 2019

Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome. d’Avignon DA, Puchalska P, Ercal B, Chang Y, Martin SE, Graham MJ, Patti GJ, Han X, Crawford PA JCI Insight. 2018 Jun 21;3(12). pii: 99762. doi: 10.1172/jci.insight.99762. [Epub ahead of print] Abstract: While several molecular targets are under consideration, mechanistic underpinnings of the transition from […]


Lipidomics reveals a systemic energy deficient state that precedes neurotoxicity in neonatal monkeys after sevoflurane exposure.

October 18, 2019

Lipidomics reveals a systemic energy deficient state that precedes neurotoxicity in neonatal monkeys after sevoflurane exposure. Wang C, Liu F, Frisch-Daiello JL, Martin S, Patterson TA, Gu Q, Liu S, Paule MG, Hanig JP, Slikker W Jr, Crawford PA, Wang C, Han X Analytica Chimica Acta. 2018 Dec 11;1037:87-96. doi: 10.1016/j.aca.2017.11.052. Epub 2017 Nov 30. […]