Current Clinical Trials in Aging Research
Studies Currently Recruiting
The purpose of the South Texas Aging Registry and Repository (STARR) is to collect health information, blood and specimens to store for future research purposes. We want to learn more about how to improve the health and quality of life of older adults. We are also working to learn how genes affect the way a person ages or how aging influences genes and the cells they affect.
You know that exercise is good for your health, but have you ever wondered why? We’re looking for men and women who are 18 years of age and older to participate in our MoTrPAC research study.
The purpose of this study is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability or heart disease.
Metformin in Alzheimer’s dementia Prevention (MAP) Study
Research study looking at whether metformin can help prevent memory decline for people with mild memory concerns.
This study aims to gather input from women aged 60 and over who are currently experiencing binge eating. We are particularly interested in how we can modify treatments to better suit the needs and lifestyles of women over 60.
Alzheimer’s Study (REACH Clinical Trial)
This trial will evaluate the use of Rapamycin to slow progression of amnestic mild cognitive impairment and early-stage Alzheimer’s.
Rapa-CV Substudy E
This study is looking for adults between the ages of 70-95 to help find out what effects Rapamycin has on heart function, heart muscle stiffening, and blood vessels.
GLP1 and Aging
This study is looking for adults older than 65 with prediabetes or diabetes to help find out what effects Semaglutide has on physical function, body composition, and aging.
- Growth Hormone Replacement Therapy in Veterans with mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD): The GRIT Study
Studies Closed to Enrollment
- Targeting Pro-Inflammatory Cells in Idiopathic Pulmonary Fibrosis: a Human Trial
- The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
- Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim1)
- Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)
- The Physiological Effects of Intranasal Oxytocin on Sarcopenic Obesity (INOSO)
- Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly
- Healthy Weight Intervention
- Effect of Stress Busting Program on Caregivers’ Quality of Life, Immunology/Stress Biomarkers and Cellular Aging
- Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer’s Disease (MB2)
- Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults
- Aspirin in Reducing Events in the Elderly Extension
- Effects of topical Rapamycin Ointment
- Effect of Behavioral Lifestyle Intervention on Frailty in Older Adults with Diabetes: A Pilot Study (Behave Study)
- A Double-blind, Placebo Controlled, Randomized INTerventional Clinical Trial (SARA-INT Study)
- Impact of Metformin on Immunity (Immune/Met Study)
- Cognition, Age and Rapamycin Effectiveness-Downregulation of the mTor Pathway (CARPE DIEM Study)
- Metformin for Preventing Frailty in High Risk Older Adults (Frailty Prevention)
- Anti-Retroviral Therapy for Alzheimer’s Disease (ART-AD)
- Effect of SGLT2 inhibition on aging-related biomarkers in older obese adults with pre-diabetes (SGLT2i)
- Topical RAPA
- Effects of Creatine Supplementation in Breast Cancer Survivors (THRIVE)