Current Clinical Trials in Aging Research


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Studies Currently Recruiting

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Frailty Prevention

The overall goal of this project is to determine whether metformin treatment prevents or reduces frailty in older adults who have pre-diabetes.

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Immune MET

Our research team is conducting a study to examine how a medication can improve the immune system in older adults and if it can improve vaccine response to the pneumonia vaccine.

An elderly couple walking together and holding hands.

SARA-INT

The purpose of this research study is to evaluate whether a medication called BIO 101 can help
1. Treat sarcopenia, including sarcopenic obesity;
2. Improve muscle function and/or muscle mass.

STARR LOGO

STARR

The purpose of the South Texas Aging Registry and Repository (STARR) is to collect health information, blood and specimens to store for future research purposes. We want to learn more about how to improve the health and quality of life of older adults. We are also working to learn how genes affect the way a person ages or how aging influences genes and the cells they affect.

A couple walking together and holding hands

Behave Study

Researchers want to see if changes in lifestyle, behaviors, and self-monitoring of diet and physical activity in older adults who have Type 2 Diabetes (T2D) may help to prevent or reduce frailty. Frailty occurs in older adults and leads people to have falls, become disabled, require nursing home placement, and have increased risk of death. T2D is one of the major risk factors for frailty. T2D is a significant problem in older adults and is known to increase the risk of future frailty.

People Excersizing on a teadmill

Exercise Science/MoTrPAC

You know that exercise is good for your health, but have you ever wondered why? We’re looking for men and women who are 18 years of age and older to participate in our MoTrPAC research study.

SToMP-AD

The underlying processes driving chronic neurodegeneration in Alzheimer’s disease (AD) and related neurodegenerative disorders are largely unknown. Moreover, individuals with AD suffer from more age-associated health conditions than other older adults without AD. This research will use a combination of oral medications (dasatinib and quercetin) in an intermittent administration regimen for 12 weeks to identify whether the treatment will reach the spinal fluid or cross the blood-brain barrier, and whether it can affect the cellular life cycle and cellular inflammation that goes with aging.

Women’s Health and Aging

We invite you to complete an online survey on women’s health and aging! Our goal is to learn more about how best to promote healthy aging among women by looking at a number of factors related to women’s health and aging, including social, lifestyle, and environmental factors.

SGLT2i

Looking for participants who are 60 and older, overweight, and have borderline diabetes. We want to evaluate the effect of the FDA approved medication dapagliflozin on the reduction of cellular damage, pro-inflammatory cells of aging and other known markers of biological aging.

Coming Soon

  • Cognition, Age, and Rapamycin Effectiveness – Downregulation of the mTOR Pathway
      • Principal Investigators:  Mitzi Gonzales, PhD, and Dean Kellogg, MD, PhD
  • Pragmatic Evaluation of Events and benefits of Lipid-lowering in Older Adults
      • Principal Investigator:  Sara Espinoza, MD, MSc
  • AntiRetroviral Therapy for Alzheimer’s Disease (ART-AD)
      • Principal Investigator:  Bess Frost, PhD
      • Co-Investigators:  Nicolas Musi, MD and Campbell Sullivan, PsyD

Studies Closed to Enrollment

All UT Health Clinical Trials