Studies Currently Recruiting
The purpose of this research study is to evaluate whether a medication called BIO 101 can help
1. Treat sarcopenia, including sarcopenic obesity;
2. Improve muscle function and/or muscle mass.
The purpose of the South Texas Aging Registry and Repository (STARR) is to collect health information, blood and specimens to store for future research purposes. We want to learn more about how to improve the health and quality of life of older adults. We are also working to learn how genes affect the way a person ages or how aging influences genes and the cells they affect.
Researchers want to see if changes in lifestyle, behaviors, and self-monitoring of diet and physical activity in older adults who have Type 2 Diabetes (T2D) may help to prevent or reduce frailty. Frailty occurs in older adults and leads people to have falls, become disabled, require nursing home placement, and have increased risk of death. T2D is one of the major risk factors for frailty. T2D is a significant problem in older adults and is known to increase the risk of future frailty.
You know that exercise is good for your health, but have you ever wondered why? We’re looking for men and women who are 18 years of age and older to participate in our MoTrPAC research study.
The underlying processes driving chronic neurodegeneration in Alzheimer’s disease (AD) and related neurodegenerative disorders are largely unknown. Moreover, individuals with AD suffer from more age-associated health conditions than other older adults without AD. This research will use a combination of oral medications (dasatinib and quercetin) in an intermittent administration regimen for 12 weeks to identify whether the treatment will reach the spinal fluid or cross the blood-brain barrier, and whether it can affect the cellular life cycle and cellular inflammation that goes with aging.
- Cognition, Age, and Rapamycin Effectiveness – Downregulation of the mTOR Pathway
- Principal Investigators: Mitzi Gonzales, PhD, and Dean Kellogg, MD, PhD
- SGLT2 Inhibition Older Obese Adults with Pre-diabetes
- Principal Investigator: Carolina Solis-Herrera, MD
- Pragmatic Evaluation of Events and benefits of Lipid-lowering in Older Adults
- Principal Investigator: Sara Espinoza, MD, MSc
Studies Closed to Enrollment
- Targeting Pro-Inflammatory Cells in Idiopathic Pulmonary Fibrosis: a Human Trial
- The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
- Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim1)
- Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)
- The Physiological Effects of Intranasal Oxytocin on Sarcopenic Obesity (INOSO)
- Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly
- Healthy Weight Intervention
- Effect of Stress Busting Program on Caregivers’ Quality of Life, Immunology/Stress Biomarkers and Cellular Aging
- Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer’s Disease (MB2)
- Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults
- Aspirin in Reducing Events in the Elderly Extension
- Effects of topical Rapamycin Ointment