Current Clinical Trials in Aging Research

Studies Currently Recruiting
Frailty Prevention
The overall goal of this project is to determine whether metformin treatment prevents or reduces frailty in older adults who have pre-diabetes.
Immune MET
Our research team is conducting a study to examine how a medication can improve the immune system in older adults and if it can improve vaccine response to the pneumonia vaccine.
STARR
The purpose of the South Texas Aging Registry and Repository (STARR) is to collect health information, blood and specimens to store for future research purposes. We want to learn more about how to improve the health and quality of life of older adults. We are also working to learn how genes affect the way a person ages or how aging influences genes and the cells they affect.
Exercise Science/MoTrPAC
You know that exercise is good for your health, but have you ever wondered why? We’re looking for men and women who are 18 years of age and older to participate in our MoTrPAC research study.
SToMP-AD
This study will evaluate the combination of two medications to see if it has effects on individuals with early Alzheimer’s disease.
Women’s Health and Aging
We invite you to complete an online survey on women’s health and aging! Our goal is to learn more about how best to promote healthy aging among women by looking at a number of factors related to women’s health and aging, including social, lifestyle, and environmental factors.
SGLT2i
Looking for participants who are 60 and older, overweight, and have borderline diabetes. We want to evaluate the effect of the FDA approved medication dapagliflozin on the reduction of cellular damage, pro-inflammatory cells of aging and other known markers of biological aging.
PREVENTABLE
The purpose of this study is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability or heart disease.
ART-AD
This study will evaluate if the medication 3TC will effectively prevent decline and loss of function in the nervous system of adults with early Alzheimer’s Disease.
Over-eating & Older Women
The purpose of this research study is to understand how experiences related to aging impact over-eating behaviors in women.
Topical RAPA
Help us find out if using RAPA ointment can slow down the aging of skin cells.
Coming Soon
- Cognition, Age, and Rapamycin Effectiveness – Downregulation of the mTOR Pathway
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- Principal Investigators: Mitzi Gonzales, PhD, and Dean Kellogg, MD, PhD
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Studies Closed to Enrollment
- Targeting Pro-Inflammatory Cells in Idiopathic Pulmonary Fibrosis: a Human Trial
- The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
- Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim1)
- Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)
- The Physiological Effects of Intranasal Oxytocin on Sarcopenic Obesity (INOSO)
- Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly
- Healthy Weight Intervention
- Effect of Stress Busting Program on Caregivers’ Quality of Life, Immunology/Stress Biomarkers and Cellular Aging
- Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer’s Disease (MB2)
- Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults
- Aspirin in Reducing Events in the Elderly Extension
- Effects of topical Rapamycin Ointment
- Effect of Behavioral Lifestyle Intervention on Frailty in Older Adults with Diabetes: A Pilot Study (Behave Study)
- A Double-blind, Placebo Controlled, Randomized INTerventional Clinical Trial (SARA-INT Study)