UT Health Newsroom: Flies, worms poorly predict drugs’ life span effects in mice, study indicates

Original story: UT Health San Antonio Newsroom

Doctoral student’s research suggests difficulty of translating longevity interventions from lower species to mammals

Contact: Will Sansom, 210-567-2579, sansom@uthscsa.edu

SAN ANTONIO (April 21, 2023) — If a drug extends the life span of worms or flies, is it likely to do the same in mice?

Not typically based on the existing data, said Michael Bene, a sixth-year doctoral student at The University of Texas Health Science Center at San Antonio.

Bene reviewed life span studies from two large databases as a side project to his doctoral research at the health science center’s Sam and Ann Barshop Institute for Longevity and Aging Studies. He is a student in the Integrated Biomedical Sciences Ph.D. program offered by the health science center’s Graduate School of Biomedical Sciences.

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