In this review, titled “Visceral adiposity, metabolic health and aging,” the authors critically evaluate whether visceral adipose tissue (VAT), commonly known as visceral fat, is simply a correlate of aging or whether it plays a direct, causal role in driving age-related metabolic decline and systemic aging processes. The authors conclude that VAT is not inherently […]

Kristi Dietert, PhD, has received an F32 Fellowship grant from the NIA for her project titled “Circadian reprogramming in cellular senescence.” Dr. Dietert is a postdoctoral fellow in the lab of Kevin Koronowski, PhD, at the Sam and Ann Barshop Institute for Longevity and Aging Studies.

Highlights: The paper reviews evidence on lifestyle-based weight loss in older adults with obesity, showing that caloric restriction reliably reduces fat mass but often leads to concurrent losses in muscle and bone. It identifies resistance training, adequate protein intake, and vitamin D supplementation as the most effective strategies to preserve musculoskeletal health during weight loss, […]

The paper, titled “Microglia-specific regulation of lipid metabolism in Alzheimer’s disease revealed by microglial depletion in 5xFAD mice,” explores how microglia, the brain’s immune cells, regulate lipid metabolism and contribute to Alzheimer’s disease progression. By studying microglial depletion in a mouse model of Alzheimer’s, the research provides new insights into how these cells influence disease […]