Barshop Institute
Category
July 29, 2026
This study shows that CELF2, an RNA-binding protein, is essential for healthy brain development. Researchers found that loss of CELF2 disrupted the organization and maturation of neurons, altered the activity of hundreds of genes, and reduced levels of CAMK2A, a key protein involved in synaptic function. The findings highlight how defects in RNA regulation can […]
July 28, 2026
Dr. Chen is the holder of the Bartell Zachry Memorial Distinguished Professorship for Research in Neurodegenerative Diseases, an Associate Professor with the Department of Cell Systems and Anatomy, and an investigator with the Sam and Ann Barshop Institute for Longevity and Aging Studies. Transcription factor condensates as storage Lizhen Chen, Zhijie Liu Nat Cell Biol. […]
July 22, 2026
Laurence Maeyens, a second-year PhD student in the Integrated Biomedical Sciences Program Biology of Aging Discipline has been selected for the Jess Hay Chancellor’s Fellowship. Laurence is co-mentored by James F. Nelson, PhD, and Shangang Zhao, PhD. Established by former University of Texas System Regent Jess Hay, the fellowship recognizes exceptional graduate students whose high-quality […]
July 1, 2026
In the paper, titled “Timed secreted proteomes reveal regulation of hepatokines by the liver circadian clock,” researchers found that the liver’s circadian clock controls the timing of protein release, identifying hundreds of proteins that are secreted differently throughout the day and help regulate metabolism. A key discovery was that the liver releases more endostatin during […]
June 1, 2026
Original story: Texas Public Radio By: Bonnie Petrie (May 31, 2026) — In 2009, a study found that rapamycin (sirolimus) could extend the lifespan of mice by 12%, and that those longer lives were also healthier. Dr. Dean Kellogg, Jr., PhD, thought, “This is too good to be true. A pill that can change aging […]
April 28, 2026
Dr. Xianlin Han has been selected as a recipient of a 2026 Presidential Excellence Award in the category of Distinguished Senior Research Scholar. Established in 1985, the Presidential Excellence Awards recognize exemplary performance by individuals who consistently excel in their positions and demonstrate a strong commitment to the mission and core values of UT San […]
April 23, 2026
Original story: UT Health San Antonio Newsroom By Claire Kowalick SAN ANTONIO (April 21, 2026) Alzheimer’s is a highly heritable disease with about 60% of the risk coming from a person’s genes. The other 40% of the risk remains less well-studied and may, in part, come from environmental stressors. The University of Texas at San […]
April 16, 2026
A recent study from the lab of Blake Rasmussen, PhD, and published in the Journal of Applied Physiology provides new insights into how heightened mTORC1 activity in muscle influences the body’s response to endurance exercise. The researchers found that while exercise improved mitochondrial activity and altered muscle lipid metabolism, excessive mTORC1 signaling limited gains in […]
April 9, 2026
Original story: UT Health San Antonio Newsroom By Claire Kowalick SAN ANTONIO (April 8, 2026) New UT San Antonio study introduces analytical tool to better hone aging interventions When scientists test potential life‑extending interventions, often the central question simply asks if the intervention works. New research from The University of Texas at San Antonio (UT […]
March 19, 2026
Original story: Texas Public Radio By: David Martin Davies (March 17, 2026) — At UT Health San Antonio’s Sam and Ann Barshop Institute, researchers are preparing a major new test of an old scientific ambition: whether medicines already on the market can help delay the biological decline that comes with aging. The study, called VITAL-H, […]
