Barshop Institute
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March 19, 2025
A new paper from the lab of David Gius, MD, PhD, and supported by the Shock Center GeroMetabolism Core, uses a novel mouse model targeting mitochondrial acetylation to identify potential functional mechanisms of ketogenic diets on lipid metabolism. Dr. Gius is a Professor of Radiation Oncology, the Assistant Dean for Research with the Joe R. […]
March 18, 2025
Congratulations to Pepper Center Core Leader Tiffany Cortes, MD, on her new paper outlining the importance of addressing lifestyle-based approaches to preserving bone and muscle with weight loss in older patients and identify best practices for doing so. Dr. Cortes is an Assistant Professor/Clinical in the Department of Medicine, Division of Endocrinology, Metabolism, and Diabetes. […]
March 12, 2025
Support from the San Antonio Nathan Shock Center Animal Core contributed to a recent publication of translation of 17α-estradiol as a gerotherapeutic intervention in non-human primates. A pilot study evaluating dosing tolerability of 17α-estradiol in male common marmosets (Callithrix jacchus) Roshini Sathiaseelan, Jose V V Isola, Roberto Santín-Márquez, Daniel Adekunbi, Michal Fornalik, Adam B Salmon, […]
March 6, 2025
David Gius, MD, PhD, professor in the Department of Radiation Oncology, received CPRIT’s individual investigator research award for clinical trials in the amount of $1,390,420 to fund a four-year, phase 2 clinical trial for women with estrogen receptor positive (ER+) breast cancer. UT Health Newsroom Press Release CPRIT Press Release
March 6, 2025
Masahiro Morita, PhD, associate professor in the Department of Molecular Medicine and a researcher with the Sam and Ann Barshop Institute for Longevity and Aging Studies at UT Health San Antonio, received a $900,000 individual investigator award from CPRIT to study how obesity increases the risk of liver cancer by investigating the mechanisms by which […]
March 4, 2025
The lab of Blake Rasmussen, PhD collaborated with the late Mike Sheetz, PhD lab to Rejuvenate Senescent Cells with low frequency ultrasound. Dr. Rasmussen is Professor and Chair of the Department of Cellular & Integrative Physiology, Director of the Center for Metabolic Health, and an investigator with the Sam And Ann Barshop Institute for Longevity […]
February 27, 2025
A new study from the lab of Blake Rasmussen, PhD has identified new functional regulators of the differences in exercise response between young and old men. These might be future targets to improve exercise output in older populations. Dr. Rasmussen is Professor and Chair of the Department of Cellular & Integrative Physiology, Director of the […]
February 26, 2025
Congratulations to the lab of Dr. David Gius. His lab’s recent publication outlines how the regulation of mitochondrial antioxidant MnSOD drives mitochondrial physiology and heart dysfunction. Dr. Gius is a Professor of Radiation Oncology, the Assistant Dean for Research with the Joe R. & Teresa Lozano Long School of Medicine, and the Associate Cancer Center […]
February 25, 2025
Newest publication from the lab of Lily Dong, PhD, identifies a new player in the regulation of metabolic function. The hormone LRG1 is a significant contributor to diet-induced diabetes in animal models and may be a promising therapeutic target. Dr. Dong is Professor and Chair of the Department of Cell Systems and Anatomy. Diet-enhanced LRG1 […]
February 21, 2025
Unsheathing the role of myelin lipids in Alzheimer’s disease By Andrea Lius Feb. 21, 2025 Alzheimer’s disease, or AD, is a devastating neurodegenerative disease that leads to irreversible cognitive decline in older adults. In the early 2000s, Xianlin Han and his colleagues found that patients with early AD had dramatically reduced levels of sulfatides, a […]
