Barshop Institute
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April 15, 2025
Anya Kalenta, a final year PhD student, has published her first first-author publication. In this study, they investigated how an acute bout of treadmill running alters the skeletal muscle metabolome and lipidome in mice with hyperactive mTORC1 signaling. Anya is a PhD student in the lab of Blake Rasmussen, PhD at the Sam and Ann […]
April 14, 2025
Biology of Aging PhD student Christopher Litwin won Best Poster Presentation in the Graduate Student category at the 2025 LSOM Research Symposium. His poster title was “Protein Secretion From Liver Ex Vivo Reveals Regulation of Hepatokines by Sex and Circadian Rhythm.” Christopher is a PhD student in the lab of Kevin Koronowski, PhD. Dr. Koronowski […]
April 7, 2025
In new research supported by the San Antonio Nathan Shock Center, Yidong Bai, PhD, shows that the structure and function of mitochondria of naked mole-rats are preserved with age. The preservation of mitochondria assembly might contribute to the extreme longevity and disease resistance of these animals. Robust assembly of electron transfer chain in the brain […]
March 31, 2025
A new publication from Daniel Adekunbi, PhD, shows that aging is associated with a significant decline in mitochondrial bioenergetics in the brain in a non-human primate model of aging. This loss of energetics is associated with a similar decline in walking speed with age, highlighting a potential mechanism for increased frailty and loss of function […]
March 27, 2025
A new study from the lab of Kevin Koronowski, PhD, looks at the effect of chronic jet lag in mice on their behavior and metabolism dysfunction in the liver. This study shows that misalignment of the normal circadian rhythm can have long-term functional consequences that may deteriorate aging health. Dr. Koronowski is an Assistant Professor […]
March 25, 2025
Dr. Kevin Koronowski is the recipient of a three-year American Heart Association Career Development Award for his project titled “Lifting the Circadian Brake on PPAR Alpha.” Dr. Koronowski is an Assistant Professor with the Department of Biochemistry and Structural Biology and an investigator with the Sam and Ann Barshop Institute for Longevity and Aging Studies.
March 21, 2025
The UT Health San Antonio Graduate School of Biomedical Sciences (GSBS) Presidential Ambassador joins the ambassadors of the other 5 schools in supporting and engaging with the Acting President. The Ambassador attends institutional functions where they represent the GSBS student body. The Ambassador is chosen for their engagement in GSBS activities, strong communication skills, and […]
March 19, 2025
A new paper from the lab of David Gius, MD, PhD, and supported by the Shock Center GeroMetabolism Core, uses a novel mouse model targeting mitochondrial acetylation to identify potential functional mechanisms of ketogenic diets on lipid metabolism. Dr. Gius is a Professor of Radiation Oncology, the Assistant Dean for Research with the Joe R. […]
March 18, 2025
Congratulations to Pepper Center Core Leader Tiffany Cortes, MD, on her new paper outlining the importance of addressing lifestyle-based approaches to preserving bone and muscle with weight loss in older patients and identify best practices for doing so. Dr. Cortes is an Assistant Professor/Clinical in the Department of Medicine, Division of Endocrinology, Metabolism, and Diabetes. […]
March 12, 2025
Support from the San Antonio Nathan Shock Center Animal Core contributed to a recent publication of translation of 17α-estradiol as a gerotherapeutic intervention in non-human primates. A pilot study evaluating dosing tolerability of 17α-estradiol in male common marmosets (Callithrix jacchus) Roshini Sathiaseelan, Jose V V Isola, Roberto Santín-Márquez, Daniel Adekunbi, Michal Fornalik, Adam B Salmon, […]