Barshop Institute
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September 21, 2025
A new study from the lab of Shangang Zhao, PhD, shows increased susceptibility of older mice to side effects when treated with liraglutide (a GLP-1 receptor agonist to treat obesity and metabolic disease). From this study, on-off cycles of this drug cause acceleration of frailty and sarcopenia. Dr. Zhao is an Assistant Professor in the […]
September 20, 2025
A new study from Ellen Kraig, PhD, and Dean Kellogg, Jr, MD, PhD, reports on the benefits of the gerotherapeutic rapamycin to cardiac and endothelial function in aging patients. This pilot study was supported by the San Antonio Claude Pepper Older Americans Independence Center. Dr. Kraig is a Professor in the Department of Cell Systems […]
September 19, 2025
A new study from the Interventions Testing Program (ITP) highlights beneficial effects on mouse lifespan with the compounds epicatechin (a plant compound in cocoa, red wine, and tea), halofuginone (a protein synthesis inhibitor) and mitoglitazone (an insulin sensitizer). The Barshop Institute is one of 3 sites that make up the ITP. Extension of lifespan by […]
September 15, 2025
Original story: UT Health San Antonio Newsroom Shared By: Claire Kowalick SAN ANTONIO (September 15, 2025) — The population of older Americans is expanding rapidly and is expected to double by 2060. While people are living longer than ever, many are also living with chronic health problems that impact their quality of life and ability […]
September 3, 2025
New NIH-funded program aims to grow pipeline of students in aging research across Texas Original story: UT Health San Antonio Newsroom Shared By: Claire Kowalick SAN ANTONIO (September 3, 2025) — A new multi-site, eight-week research program aims to engage first-year medical students interested in aging medicine. The Sam and Ann Barshop Institute for Longevity […]
August 29, 2025
Dr. Juan Pablo Palavicini has received a Rising UT STAR retention award for $150,000. The STARs (Science and Technology Acquisition and Retention) Program provides funding to help purchase state-of-the-art equipment and make necessary laboratory/facility renovations to support faculty members in performing their research. Dr. Palavicini is an assistant professor in the Department of Cellular and […]
August 28, 2025
Original story: UT Health San Antonio Newsroom Estrogen may be protective against adverse effects Contact: Steven Lee, (210) 450-3823, lees22@uthscsa.edu SAN ANTONIO (August 28, 2025) — Could a keto diet affect males differently from females? A study from The University of Texas Health Science at San Antonio (UT Health San Antonio) suggests so, and estrogen […]
August 28, 2025
Study Highlights Sex-Specific Impact of Keto Diet A recent study from the lab of David Gius, MD, PhD, and published in Cell Reports reveals that a long-term ketogenic diet leads to the accumulation of aging (senescent) cells and oxidative stress—but only in male mice. Female mice did not show these harmful effects. Interestingly, treating male […]
August 27, 2025
Nisi Jiang, PhD, first author and recent Biology of Aging IBMS graduate under the mentorship of James Nelson, PhD, led the first-ever comprehensive review of anti-aging compounds tested by the National Institute on Aging’s Interventions Testing Program. Published in the Journal of Gerontology: Biological Science (July 2025), the landmark study analyzed two decades of data […]
August 25, 2025
Original story: Texas Public Radio By: Bonnie Petrie (August 24, 2025) — A recent review of two decades of research from the National Institute on Aging (NIA) highlighted 13 anti-aging medications that show promise in preclinical studies for significantly extending lifespan. More than that, they seem to improve the quality of those extra years. There’s […]
