Congratulations to the Interventions Testing Program on their publication in Geroscience!

September 19, 2025

A new study from the Interventions Testing Program (ITP) highlights beneficial effects on mouse lifespan with the compounds epicatechin (a plant compound in cocoa, red wine, and tea), halofuginone (a protein synthesis inhibitor) and mitoglitazone (an insulin sensitizer). The Barshop Institute is one of 3 sites that make up the ITP. Extension of lifespan by […]


UT Health Newsroom: San Antonio Pepper Center secures $6.5M grant to advance aging research

September 15, 2025

Original story: UT Health San Antonio Newsroom Shared By: Claire Kowalick SAN ANTONIO (September 15, 2025) ­— The population of older Americans is expanding rapidly and is expected to double by 2060. While people are living longer than ever, many are also living with chronic health problems that impact their quality of life and ability […]


UT Health Newsroom: Inaugural cohort completes UT-MSTAR summer research program

September 3, 2025

New NIH-funded program aims to grow pipeline of students in aging research across Texas Original story: UT Health San Antonio Newsroom Shared By: Claire Kowalick SAN ANTONIO (September 3, 2025) ­— A new multi-site, eight-week research program aims to engage first-year medical students interested in aging medicine. The Sam and Ann Barshop Institute for Longevity […]


Congratulations to Juan Pablo Palavicini, PhD, on his Rising UT STAR Award!

August 29, 2025

Dr. Juan Pablo Palavicini has received a Rising UT STAR retention award for $150,000. The STARs (Science and Technology Acquisition and Retention) Program provides funding to help purchase state-of-the-art equipment and make necessary laboratory/facility renovations to support faculty members in performing their research.  Dr. Palavicini is an assistant professor in the Department of Cellular and […]

Juan Pablo Palavicini, PhD


UT Health Newsroom: A keto diet might benefit females more than males, a new UT Health San Antonio study suggests

August 28, 2025

Original story: UT Health San Antonio Newsroom Estrogen may be protective against adverse effects Contact: Steven Lee, (210) 450-3823, lees22@uthscsa.edu SAN ANTONIO (August 28, 2025) ­— Could a keto diet affect males differently from females? A study from The University of Texas Health Science at San Antonio (UT Health San Antonio) suggests so, and estrogen […]


Congratulations to David Gius, MD, PhD, and his lab on their publication in Cell Reports!

August 28, 2025

Study Highlights Sex-Specific Impact of Keto Diet A recent study from the lab of David Gius, MD, PhD, and published in Cell Reports reveals that a long-term ketogenic diet leads to the accumulation of aging (senescent) cells and oxidative stress—but only in male mice. Female mice did not show these harmful effects. Interestingly, treating male […]




Congratulations to Nisi Jiang, PhD, on his landmark publication in Journal of Gerontology: Biological Science

August 27, 2025

Nisi Jiang, PhD, first author and recent Biology of Aging IBMS graduate under the mentorship of James Nelson, PhD, led the first-ever comprehensive review of anti-aging compounds tested by the National Institute on Aging’s Interventions Testing Program. Published in the Journal of Gerontology: Biological Science (July 2025), the landmark study analyzed two decades of data […]




Texas Public Radio: Science & Medicine: An anti-aging medication that may work for women, too

August 25, 2025

Original story: Texas Public Radio By: Bonnie Petrie (August 24, 2025) ­— A recent review of two decades of research from the National Institute on Aging (NIA) highlighted 13 anti-aging medications that show promise in preclinical studies for significantly extending lifespan. More than that, they seem to improve the quality of those extra years. There’s […]

Dr. James Nelson



Congratulations to Sanjay Kureel, PhD, on his publication in Aging and Disease!

August 15, 2025

Highlights: This review explores ferroptosis, an iron-dependent, non-apoptotic form of programmed cell death, as a promising strategy for eliminating senescent cells, which accumulate with age and contribute to tissue dysfunction and age-related diseases such as fibrosis, atherosclerosis, osteoarthritis, and neurodegeneration. The molecular mechanisms of ferroptosis, including iron overload, lipid peroxidation, and oxidative damage, can be […]