A new study from the lab of Shangang Zhao, PhD, shows increased susceptibility of older mice to side effects when treated with liraglutide (a GLP-1 receptor agonist to treat obesity and metabolic disease). From this study, on-off cycles of this drug cause acceleration of frailty and sarcopenia.  Dr. Zhao is an Assistant Professor in the […]

A new study from Ellen Kraig, PhD, and Dean Kellogg, Jr, MD, PhD, reports on the benefits of the gerotherapeutic rapamycin to cardiac and endothelial function in aging patients. This pilot study was supported by the San Antonio Claude Pepper Older Americans Independence Center.  Dr. Kraig is a Professor in the Department of Cell Systems […]

Dr. Juan Pablo Palavicini has received a Rising UT STAR retention award for $150,000. The STARs (Science and Technology Acquisition and Retention) Program provides funding to help purchase state-of-the-art equipment and make necessary laboratory/facility renovations to support faculty members in performing their research.  Dr. Palavicini is an assistant professor in the Department of Cellular and […]

Study Highlights Sex-Specific Impact of Keto Diet A recent study from the lab of David Gius, MD, PhD, and published in Cell Reports reveals that a long-term ketogenic diet leads to the accumulation of aging (senescent) cells and oxidative stress—but only in male mice. Female mice did not show these harmful effects. Interestingly, treating male […]

Nisi Jiang, PhD, first author and recent Biology of Aging IBMS graduate under the mentorship of James Nelson, PhD, led the first-ever comprehensive review of anti-aging compounds tested by the National Institute on Aging’s Interventions Testing Program. Published in the Journal of Gerontology: Biological Science (July 2025), the landmark study analyzed two decades of data […]