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Congratulations to Dr. Miranda Orr for her publication in Aging Cell
Tau protein aggregation is associated with cellular senescence in the brain. Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME Aging Cell. 2018 Aug 20:e12840. doi: 10.1111/acel.12840. [Epub ahead of print] Abstract: Tau protein accumulation is the most common pathology among degenerative brain diseases, including Alzheimer’s disease (AD), progressive supranuclear […]
Read moreCongratulations to Dr. Yuji Ikeno for his publication in Geroscience
Thioredoxin overexpression in both the cytosol and mitochondria accelerates age-related disease and shortens lifespan in male C57BL/6 mice. Cunningham GM, Flores LC, Roman MG, Cheng C, Dube S, Allen C, Valentine JM, Hubbard GB, Bai Y, Saunders TL, Ikeno Y Geroscience. 2018 Aug 18. doi: 10.1007/s11357-018-0039-6. [Epub ahead of print] Abstract: To investigate the role […]
Read moreCongratulations to Dr. Veronica Galvan for her publication in American Journal of Physiology-Heart and Circulatory Physiology
Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment. Van Skike CE, Jahrling JB, Olson AB, Sayre NL, Hussong SA, Ungvari Z, Lechleiter JD, Galvan V Am J Physiol Heart Circ Physiol. 2018 Apr 1;314(4):H693-H703. doi: 10.1152/ajpheart.00570.2017. Epub 2017 Dec 22. Abstract: An intact blood-brain barrier (BBB) limits […]
Read moreThe Source: UT Health Barshop Institute Battles Consequences Of Aging
“Just because you are getting older doesn’t mean you have to deal with problems related to old age. Some of the world’s leading research on how to fight the consequences of aging is happening here in San Antonio at UT Health’s Barshop Institute for Longevity and Aging Studies. What have researchers and scientists discovered about treating […]
Read moreAbnormal gene copying seen in tauopathy fruit fly models
Congratulations to Dr. Bess Frost on her new publication in Nature Neuroscience, “Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies.” The Frost laboratory studies fundamental processes in cell biology that drive neurodegeneration and employs a multi-system approach to rapidly identify, test, and validate hypotheses. The study, which was spearheaded […]
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