Congratulations to Christopher Litwin on his first, first-authored paper, published in Nature Communications!

July 1, 2026

In the paper, titled “Timed secreted proteomes reveal regulation of hepatokines by the liver circadian clock,” researchers found that the liver’s circadian clock controls the timing of protein release, identifying hundreds of proteins that are secreted differently throughout the day and help regulate metabolism.  A key discovery was that the liver releases more endostatin during […]



UT Health Newsroom: Timing matters in longevity research

April 9, 2026

Original story: UT Health San Antonio Newsroom By Claire Kowalick SAN ANTONIO (April 8, 2026) New UT San Antonio study introduces analytical tool to better hone aging interventions When scientists test potential life‑extending interventions, often the central question simply asks if the intervention works. New research from The University of Texas at San Antonio (UT […]



Congratulations to Laurence Maeyens on his first-authored publication in Nature Aging!

February 27, 2026

In this review, titled “Visceral adiposity, metabolic health and aging,” the authors critically evaluate whether visceral adipose tissue (VAT), commonly known as visceral fat, is simply a correlate of aging or whether it plays a direct, causal role in driving age-related metabolic decline and systemic aging processes. The authors conclude that VAT is not inherently […]



Congratulations to Tiffany Cortes, MD, on her publication in Obesity!

November 21, 2025

Highlights: The paper reviews evidence on lifestyle-based weight loss in older adults with obesity, showing that caloric restriction reliably reduces fat mass but often leads to concurrent losses in muscle and bone. It identifies resistance training, adequate protein intake, and vitamin D supplementation as the most effective strategies to preserve musculoskeletal health during weight loss, […]



Congratulations to Ziying Xu on her first, first-authored research paper, published in Nature Communications!

October 23, 2025

The paper, titled “Microglia-specific regulation of lipid metabolism in Alzheimer’s disease revealed by microglial depletion in 5xFAD mice,” explores how microglia, the brain’s immune cells, regulate lipid metabolism and contribute to Alzheimer’s disease progression. By studying microglial depletion in a mouse model of Alzheimer’s, the research provides new insights into how these cells influence disease […]



Congratulations to Shangang Zhao, PhD, and lab on their publication in Aging Cell!

September 21, 2025

A new study from the lab of Shangang Zhao, PhD, shows increased susceptibility of older mice to side effects when treated with liraglutide (a GLP-1 receptor agonist to treat obesity and metabolic disease). From this study, on-off cycles of this drug cause acceleration of frailty and sarcopenia.  Dr. Zhao is an Assistant Professor in the […]



Congratulations to the Interventions Testing Program on their publication in Geroscience!

September 19, 2025

A new study from the Interventions Testing Program (ITP) highlights beneficial effects on mouse lifespan with the compounds epicatechin (a plant compound in cocoa, red wine, and tea), halofuginone (a protein synthesis inhibitor) and mitoglitazone (an insulin sensitizer). The Barshop Institute is one of 3 sites that make up the ITP. Extension of lifespan by […]