Barshop Institute
May 15, 2024
Original story: UT Health San Antonio Newsroom MoTrPAC releases seven publications this month We all know that exercise is good for us, but figuring out the “why” and “how” of physical exercise’s effect on the body is the goal of a 10-year, multi-million dollar project through the National Institutes of Health called the Molecular Transducers […]
May 3, 2024
Dr. Koronowski is an Assistant Professor with the Sam and Ann Barshop Institute for Longevity and Aging Studies and the Department of Biochemistry and Structural Biology. Brain-muscle communication prevents muscle aging by maintaining daily physiology Arun Kumar, Mireia Vaca-Dempere, Thomas Mortimer, Oleg Deryagin, Jacob G Smith, Paul Petrus, Kevin B Koronowski, Carolina M Greco, Jessica […]
May 2, 2024
Nisi Jiang is a PhD student in the Biology of Aging discipline under the mentorship of Dr. James Nelson. The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride Nisi Jiang, Jonathan Gelfond, Qianqian Liu, Randy […]
February 13, 2024
Dr. Shi is the Joe R. and Teresa Lozano Long Distinguished Chair in Metabolic Biology and a Professor with the Department of Pharmacology and the Sam and Ann Barshop Institute for Longevity and Aging Studies. An upstream open reading frame (5′-uORF) links oxidative stress to translational control of ALCAT1 through phosphorylation of eIF2α Jun Zhang […]
November 27, 2023
Dr. Zhao is an assistant professor in the Department of Medicine, Division of Endocrinology and an investigator with the Sam and Ann Barshop Institute for Longevity and Aging Studies. Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders Shangang Zhao, Qian Lin, Wei Xiong, Li Li, Leon Straub, Dinghong Zhang, Rizaldy Zapata, Qingzhang Zhu, Xue-Nan […]
October 31, 2023
The paper will be a spotlight article with a preview in an upcoming issue. Dr. Shi is the Joe R. and Teresa Lozano Long Distinguished Chair in Metabolic Biology and a Professor with the Department of Pharmacology and the Sam and Ann Barshop Institute for Longevity and Aging Studies. LPGAT1 controls MEGDEL syndrome by coupling […]
October 4, 2023
Original story: UT Health San Antonio Newsroom Lower levels of a protective protein lead to liver inflammation, scarring Contact: Will Sansom, 210-567-2579, sansom@uthscsa.edu SAN ANTONIO (Oct. 3, 2023) — Researchers at The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) have identified a molecular pathway that connects aging […]
September 22, 2023
Dr. Chen is an Associate Professor with the Sam and Ann Barshop Institute for Longevity and Aging Studies and the Department of Cell Systems and Anatomy. Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactions Lizhen Chen, Zhao Zhang, Qinyu Han, Barun K. Maity, Leticia Rodrigues, Emily Zboril, Rashmi Adhikari, Su-Hyuk Ko, […]
August 16, 2023
Dr. Frost is an Associate Professor with the Sam and Ann Barshop Institute for Longevity and Aging Studies, the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Disorders, and the Department of Cell Systems and Anatomy. She is the holder/manager of the Bartell Zachry Distinguished Professor for Research in Neurodegenerative Disorders. Alzheimer’s disease and related tauopathies: […]
July 26, 2023
Original story: UT Health San Antonio Newsroom Splicing deregulation is potential drug target and diagnostic tool Alcohol consumption is a major cause of chronic liver disease. The disease, which has devastating consequences, progresses through stages of hepatitis (inflammation), fibrosis (scarring) and cirrhosis (severe scarring). Advanced disease increases the risk of developing liver cancer, and some […]