UT Health Newsroom: A keto diet might benefit females more than males, a new UT Health San Antonio study suggests

Study Highlights Sex-Specific Impact of Keto Diet A recent study from the lab of David Gius, MD, PhD, and published in Cell Reports reveals that a long-term ketogenic diet leads to the accumulation of aging (senescent) cells and oxidative stress—but only in male mice. Female mice did not show these harmful effects. Interestingly, treating male […]

Nisi Jiang, PhD, first author and recent Biology of Aging IBMS graduate under the mentorship of James Nelson, PhD, led the first-ever comprehensive review of anti-aging compounds tested by the National Institute on Aging’s Interventions Testing Program. Published in the Journal of Gerontology: Biological Science (July 2025), the landmark study analyzed two decades of data […]

Highlights: This review explores ferroptosis, an iron-dependent, non-apoptotic form of programmed cell death, as a promising strategy for eliminating senescent cells, which accumulate with age and contribute to tissue dysfunction and age-related diseases such as fibrosis, atherosclerosis, osteoarthritis, and neurodegeneration. The molecular mechanisms of ferroptosis, including iron overload, lipid peroxidation, and oxidative damage, can be […]

Study Highlights Skeletal Muscle Changes During Disuse and Rehabilitation A recent study from the lab of Blake Rasmussen, PhD, and published in Physiological Reports examined how short-term skeletal muscle disuse and subsequent rehabilitation affect muscle function and gene expression in healthy middle-aged adults. Participants underwent seven days of unilateral lower-limb suspension followed by a two-week […]

A review from Biology of Aging PhD student Christopher Litwin addresses the role of the liver in regulating circadian rhythm and metabolism.  Christopher is a PhD student in the lab of Kevin Koronowski, PhD. Dr. Koronowski is an Assistant Professor with the Department of Biochemistry and Structural Biology and a Principal Investigator with the Sam […]

A new study from Barshop Investigators Ellen Kraig, PhD, and Dean Kellogg, Jr, MD, PhD, examines targeting the biology of aging with rapamycin to treat Alzheimer’s disease in a pilot clinical trial.  Dr. Kraig is a Professor in the Department of Cell Systems and Anatomy.  Dr. Kellogg is a Professor in the Department of Medicine, […]

Erik Marchant, a third year PhD student, has published his first paper from his dissertation. Erik used low-frequency ultrasound in old mice with insulin resistance and diabetes and discovered many interesting transcriptomic changes in skeletal muscle that reduce inflammation and alter immune cell function. Erik is a PhD student in the lab of Blake Rasmussen, […]