Barshop Institute
February 13, 2024
Dr. Shi is the Joe R. and Teresa Lozano Long Distinguished Chair in Metabolic Biology and a Professor with the Department of Pharmacology and the Sam and Ann Barshop Institute for Longevity and Aging Studies. An upstream open reading frame (5′-uORF) links oxidative stress to translational control of ALCAT1 through phosphorylation of eIF2α Jun Zhang […]
November 27, 2023
Dr. Zhao is an assistant professor in the Department of Medicine, Division of Endocrinology and an investigator with the Sam and Ann Barshop Institute for Longevity and Aging Studies. Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders Shangang Zhao, Qian Lin, Wei Xiong, Li Li, Leon Straub, Dinghong Zhang, Rizaldy Zapata, Qingzhang Zhu, Xue-Nan […]
October 31, 2023
The paper will be a spotlight article with a preview in an upcoming issue. Dr. Shi is the Joe R. and Teresa Lozano Long Distinguished Chair in Metabolic Biology and a Professor with the Department of Pharmacology and the Sam and Ann Barshop Institute for Longevity and Aging Studies. LPGAT1 controls MEGDEL syndrome by coupling […]
October 4, 2023
Original story: UT Health San Antonio Newsroom Lower levels of a protective protein lead to liver inflammation, scarring Contact: Will Sansom, 210-567-2579, sansom@uthscsa.edu SAN ANTONIO (Oct. 3, 2023) — Researchers at The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) have identified a molecular pathway that connects aging […]
September 22, 2023
Dr. Chen is an Associate Professor with the Sam and Ann Barshop Institute for Longevity and Aging Studies and the Department of Cell Systems and Anatomy. Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactions Lizhen Chen, Zhao Zhang, Qinyu Han, Barun K. Maity, Leticia Rodrigues, Emily Zboril, Rashmi Adhikari, Su-Hyuk Ko, […]
August 16, 2023
Dr. Frost is an Associate Professor with the Sam and Ann Barshop Institute for Longevity and Aging Studies, the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Disorders, and the Department of Cell Systems and Anatomy. She is the holder/manager of the Bartell Zachry Distinguished Professor for Research in Neurodegenerative Disorders. Alzheimer’s disease and related tauopathies: […]
July 26, 2023
Original story: UT Health San Antonio Newsroom Splicing deregulation is potential drug target and diagnostic tool Alcohol consumption is a major cause of chronic liver disease. The disease, which has devastating consequences, progresses through stages of hepatitis (inflammation), fibrosis (scarring) and cirrhosis (severe scarring). Advanced disease increases the risk of developing liver cancer, and some […]
July 25, 2023
Dr. Zang is a Professor with the Sam and Ann Barshop Institute for Longevity and Aging Studies and the Department of Molecular Medicine. She is the Ewing Halsell Distinguished Chair in Research and the Associate Director of the MD/PhD Program at UT Health San Antonio. Importantly, this paper has established a fruitful collaboration with esteemed […]
July 3, 2023
Kevin Thyne, PhD is a postdoctoral fellow in the lab of Adam Salmon, PhD with the Sam and Ann Barshop Institute for Longevity and Aging Studies. Sexually dimorphic effects of methionine sulfoxide reductase A (MsrA) on murine longevity and health span during methionine restriction Kevin M. Thyne & Adam B. Salmon Geroscience. 2023 Jun 30. […]
April 21, 2023
Original story: UT Health San Antonio Newsroom Doctoral student’s research suggests difficulty of translating longevity interventions from lower species to mammals Contact: Will Sansom, 210-567-2579, sansom@uthscsa.edu SAN ANTONIO (April 21, 2023) — If a drug extends the life span of worms or flies, is it likely to do the same in mice? Not typically based […]
