Barshop Institute
The purpose of this study is to identify proteins in the blood that drive age-related changes in our internal clock, which are known to contribute to disease. We are hoping that this research may lead to finding new therapeutic targets to improve health in aging.
This study is looking at how a medication called tirzepatide (brand names include Zepbound and Mounjaro) affects muscle strength, heart health, and metabolism in older adults with obesity. As people age, especially with obesity, they can lose strength and mobility. The goal of this study is to see whether this medication can help improve physical function and overall heart health, which may lead to better treatment options in the future.
This research will create and validate a comprehensive musculoskeletal screening tool to quantify predictors of musculoskeletal peak performance and duty-limiting musculoskeletal injuries in mid-career elite Tactical Athletes.
As the population in the U.S. continues to age, conditions such as heart disease, diabetes, and obesity are becoming more common, especially in South Texas. These conditions can increase the risk of heart problems later in life, but it is not always clear who is at highest risk. The purpose of this study is to better understand how aging, type 2 diabetes, and obesity affect heart health, and how simple exercise-related changes in blood pressure and heart rate may help identify future risk of heart disease.
This study is focused on one such family of drugs, called mTOR inhibitors. We will test two of these drugs in healthy older adults to find a protocol that can be used safely.
To facilitate aging research by creating a resource of data and biological specimens that is representative of the diverse South Texas community, with an emphasis on underrepresented groups in aging research. This resource will be made available to researchers studying aging and related health issues.
The purpose of this research study is to evaluate a new experimental device called an ultrasound bath. This device uses low-frequency ultrasound (a type of sound wave) delivered through water to determine whether it may improve muscle and physical function in older adults.
The purpose of this study is to evaluate whether long-term side effects from the virus that causes COVID-19 infection affects physical function and cells named senescent cells (a cell that ages and permanently stops dividing but does not die). Additionally, we will evaluate interventions in those with a body mass index > 30 to determine if these intervention might have a positive effect on whole body function.
This study aims to determine the effects of aerobic exercise as a primer to add-on virtual reality (VR)-based rehabilitation on balance and postural control and neuroplasticity (ability of brain to adapt in structure and function) in those with Parkinson’s disease.
The purpose of this study is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability or heart disease.