Ultrasound and Aging

The purpose of this research study is to evaluate a new experimental device called an ultrasound bath. This device uses low-frequency ultrasound (a type of sound wave) delivered through water to determine whether it may improve muscle and physical function in older adults. Earlier studies suggest that this type of ultrasound may help refresh aging cells, improve physical function, and reduce certain types of inflammation in muscle. Ultrasound treatment could become a new way to support healing in the body and may offer several advantages. It may have little to no effect on nearby healthy tissues and is unlikely to interfere with other treatments you may be receiving. We do not yet know whether this device is safe or effective. This study is being conducted to help determine the tolerability (how well it is tolerated) and effectiveness of this treatment and to better understand its effects on the body. Overall, the researchers hope to identify potential therapies that may help extend their health span in older adults.

To determine whether 8 weeks of water-based ultrasound exposure improves muscle function in older adults compared to a sham (inactive) control group.

• To evaluate the effects of ultrasound exposure on overall physical function and mobility.
• To explore whether ultrasound exposure affects cognitive function scores.
• To assess whether ultrasound exposure influences body composition, including lean mass and fat mass.

• Are 70 years of age or older
• Have a body mass index (BMI) less than 40
• Are able to walk up a flight of stairs and get in and out of a bath independently
• Have not had a heart attack or stroke within the past year
• Are willing to attend bath treatments three times per week for 8 weeks
• Are willing to undergo blood draws

• Have poor wound healing
• Have any uncontrolled medical conditions, as determined by your physician
• Have uncontrolled high blood pressure (for example, 180/100 mmHg or higher)
• Currently have rashes, open sores, boils, or infected wounds
• Have uncontrolled diabetes
• Have had an infection with antibiotic-resistant bacteria within the past 3 months

~ 3 months

• Pre-screening
• Informed consent
• Medical history
• Demographics
• Physical Exam/assessment
• Vitals
• Blood draw
• Cognitive testing
• Physical function measures
• DEXA scan
• Spa treatment (with ultrasound or without)

You may earn up to $500 for completing all study-related visits.

UT Health San Antonio
Sam and Ann Barshop Institute for Longevity and Aging Studies
4939 Charles Katz Dr.
San Antonio, TX 78229

• Thank you for your interest in one of our studies! Please complete this form and we will contact you to let you know more about this study.

Principal Investigator:
Blake B. Rasmussen, PhD