Closed and Completed Studies

Targeting Pro-Inflammatory Cells in Idiopathic Pulmonary Fibrosis: a Human Trial
The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim1)
Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)
The Physiological Effects of Intranasal Oxytocin on Sarcopenic Obesity (INOSO)
Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly
Healthy Weight Intervention
Effect of Stress Busting Program on Caregivers’ Quality of Life, Immunology/Stress Biomarkers and Cellular Aging
Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer’s Disease (MB2)
Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults
Aspirin in Reducing Events in the Elderly Extension
Effects of topical rapamycin on keloid progression
Effect of Behavioral Lifestyle Intervention on Frailty in Older Adults with Diabetes: A Pilot Study (Behave Study)
A Double-blind, Placebo Controlled, Randomized INTerventional Clinical Trial (SARA-INT Study)
Impact of Metformin on Immunity (Immune/Met Study)
ClinicalTrials.gov ID: NCT03713801
Cognition, Age and Rapamycin Effectiveness-Downregulation of the mTor Pathway (CARPE DIEM Study)
Metformin for Preventing Frailty in High Risk Older Adults (Frailty Prevention)
Anti-Retroviral Therapy for Alzheimer’s Disease (ART-AD)
PMID: 38464267
Effect of SGLT2 inhibition on aging-related biomarkers in older obese adults with pre-diabetes (SGLT2i)
Topical-RAPA Use in Inflammation Reversal and RE-setting the Epigenetic clock (Topical-RAPA)
Effects of Creatine Supplementation in Breast Cancer Survivors (THRIVE)
ClinicalTrials.gov ID: NCT04207359
PMID: 35363152
GLP1 and Aging
Metformin in Alzheimer’s dementia Prevention (MAP) Study
A senior center based multilevel lifestyle intervention to improve physical function in older adults with type 2 diabetes (RESILIENT)
Effect of mirabegron on cognition for neurogenic bladder
Mechanisms to Reduce Mental and Physical Fatigue Following Exercise Training in Older Adults (BCAA)
ClinicalTrials.gov ID: NCT05484661.
PMID: 37910166
Nutritional Optimization and Bone Health Management for Older Adults Undergoing Hip Fracture Surgery
Behavioral intervention to promote healthy nutrition in older women
The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition (NAD).
PMID: 37994989
Effect of Behavioral Lifestyle Intervention on Frailty in Older Adults With Diabetes
PMID: 35122094
Metformin to improve vaccine response in the elderly
Senolytic Therapy to Modulate Progression of Alzheimer's Disease (SToMP-AD)
ClinicalTrials.gov ID: NCT04063124
PMID: 35098970
Effect or prehabilitation blood-flow restriction training on muscle function in older adults with knee osteoarthritis awaiting total knee replacement
Physical activity intervention in older veterans
Role of TLR4 on lipid-induced insulin resistance (R01-NIDDK)
Diabetes Prevention Program Outcomes Study (DPPOS)
Promotion of successful weight management in obese veterans
PMID: 38104857
GeroFit Expansion to South Texas Veterans Health Care System
South Texas Aging Research Repository (STARR)
ClinicalTrials.gov ID: NCT05835388
Binge Eating Spectrum Treatment in Older Women (BESTOW)
ClinicalTrials.gov ID: NCT05806788
SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit
Aging Sen: Single nuclei RNA-seq to map adipose cellular populations and senescent cells with aging
Cellular effects of Fasting Mimicking Diet in Humans: an Interventional, Randomized, Open label, Parallel Assignment study