News
Congratulations to Blake Rasmussen, PhD and lab on their publication in Geroscience!
February 27, 2025
A new study from the lab of Blake Rasmussen, PhD has identified new functional regulators of the differences in exercise response between young and old men. These might be future targets to improve exercise output in older populations. Dr. Rasmussen is Professor and Chair of the Department of Cellular & Integrative Physiology, Director of the […]
Congratulations to David Gius, MD, PhD and his lab on their publication in Free Radical Biology and Medicine!
February 26, 2025
Congratulations to the lab of Dr. David Gius. His lab’s recent publication outlines how the regulation of mitochondrial antioxidant MnSOD drives mitochondrial physiology and heart dysfunction. Dr. Gius is a Professor of Radiation Oncology, the Assistant Dean for Research with the Joe R. & Teresa Lozano Long School of Medicine, and the Associate Cancer Center […]
Congratulations to Lily Dong, PhD and lab on their publication in Diabetologia!
February 25, 2025
Newest publication from the lab of Lily Dong, PhD, identifies a new player in the regulation of metabolic function. The hormone LRG1 is a significant contributor to diet-induced diabetes in animal models and may be a promising therapeutic target. Dr. Dong is Professor and Chair of the Department of Cell Systems and Anatomy. Diet-enhanced LRG1 […]
ASBMB Today: Unsheathing the role of myelin lipids in Alzheimer’s disease
February 21, 2025
Unsheathing the role of myelin lipids in Alzheimer’s disease By Andrea Lius Feb. 21, 2025 Alzheimer’s disease, or AD, is a devastating neurodegenerative disease that leads to irreversible cognitive decline in older adults. In the early 2000s, Xianlin Han and his colleagues found that patients with early AD had dramatically reduced levels of sulfatides, a […]
Congratulations to Ann Griffith, PhD and lab on their new publication in Nature Aging!
February 19, 2025
Congratulations to the lab of Dr. Ann Griffith. Their work demonstrates how the thymus is protected during aging by FGF21, providing potential targets for immune aging. Dr. Griffith is an Assistant Professor in the Department of Microbiology, Immunology & Molecular Genetics. Paracrine FGF21 dynamically modulates mTOR signaling to regulate thymus function across the lifespan Sarah […]
Congratulations to Daohong Zhou, MD and his team on their publication in Nature Aging!
February 14, 2025
The manuscript, “A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice,” was published in Nature Aging. In the paper, they reported the discovery of the first liver tropic senolytic BCL-xL and BCL-2 PROTAC 753b, which can selectively reduce senescent cells in the liver in aged mice and […]
Congratulations to Shangang Zhao, PhD on his Presidential Excellence Award!
February 7, 2025
Dr. Shangang Zhao has been selected as a recipient of a 2025 Presidential Excellence Award in the category of Junior Research Scholar. Established in 1985, the Presidential Awards recognize exemplary performance by individuals who consistently excel in their positions and demonstrate a strong commitment to the mission and core values of UT Health San Antonio. […]
Congratulations to Xianlin Han, PhD and Sijia He, PhD for their new study in Advanced Science!
February 5, 2025
The outcomes of this study suggest that targeting the cGAS-STING signaling pathway is a potential therapeutic strategy for Alzheimer’s disease. Dr. Xianlin Han is a professor in the Department of Medicine, Division of Diabetes and an investigator with the Sam and Ann Barshop Institute for Longevity and Aging Studies. Dr. Sijia He is an Assistant […]
Congratulations to Shangang Zhao, PhD and lab on their publication in Cell Reports!
January 28, 2025
Their study characterizes the role of adiponectin in the development of age-related liver fibrosis. Dr. Zhao is an assistant professor in the Department of Medicine, Division of Endocrinology and an investigator with the Sam and Ann Barshop Institute for Longevity and Aging Studies. The adiponectin-PPARγ axis in hepatic stellate cells regulates liver fibrosis Shangang Zhao, […]
Congratulations to Lizhen Chen, PhD and lab on their publication in Nature Communications!
January 27, 2025
Their study identifies the process of ferroptosis as a potential target to preserve neuronal function and innervation with aging. Dr. Chen is the holder of the Bartell Zachry Memorial Distinguished Professorship for Research in Neurodegenerative Diseases, an Associate Professor with the Department of Cell Systems and Anatomy, and an investigator with the Sam and Ann […]