Publications


UT Health Newsroom: Study: Physical exercise impacts every type of tissue in the body and affects males and females differently

May 15, 2024

Original story: UT Health San Antonio Newsroom MoTrPAC releases seven publications this month We all know that exercise is good for us, but figuring out the “why” and “how” of physical exercise’s effect on the body is the goal of a 10-year, multi-million dollar project through the National Institutes of Health called the Molecular Transducers […]




Congratulations to Nisi Jiang on his first-author publication in Geroscience!

May 2, 2024

Nisi Jiang is a PhD student in the Biology of Aging discipline under the mentorship of Dr. James Nelson. The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride Nisi Jiang, Jonathan Gelfond, Qianqian Liu, Randy […]




Congratulations to Roger Shi, PhD on his publication in Free Radical Biology and Medicine!

February 13, 2024

Dr. Shi is the Joe R. and Teresa Lozano Long Distinguished Chair in Metabolic Biology and a Professor with the Department of Pharmacology and the Sam and Ann Barshop Institute for Longevity and Aging Studies. An upstream open reading frame (5′-uORF) links oxidative stress to translational control of ALCAT1 through phosphorylation of eIF2α Jun Zhang […]




Congratulations to Shangang Zhao, PhD on his first-author publication in Science Translation Medicine!

November 27, 2023

Dr. Zhao is an assistant professor in the Department of Medicine, Division of Endocrinology and an investigator with the Sam and Ann Barshop Institute for Longevity and Aging Studies. Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders Shangang Zhao, Qian Lin, Wei Xiong, Li Li, Leon Straub, Dinghong Zhang, Rizaldy Zapata, Qingzhang Zhu, Xue-Nan […]




Congratulations to Roger Shi, PhD and the Shi Lab on their upcoming publication in Cell Reports!

October 31, 2023

The paper will be a spotlight article with a preview in an upcoming issue.  Dr. Shi is the Joe R. and Teresa Lozano Long Distinguished Chair in Metabolic Biology and a Professor with the Department of Pharmacology and the Sam and Ann Barshop Institute for Longevity and Aging Studies. LPGAT1 controls MEGDEL syndrome by coupling […]




UT Health Newsroom: Barshop Institute team discovers why liver disease is more severe in older people

October 4, 2023

Original story: UT Health San Antonio Newsroom Lower levels of a protective protein lead to liver inflammation, scarring Contact: Will Sansom, 210-567-2579, sansom@uthscsa.edu SAN ANTONIO (Oct. 3, 2023) ­— Researchers at The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) have identified a molecular pathway that connects aging […]




Congratulations to Lizhen Chen, PhD on her publication in Molecular Cell!

September 22, 2023

Dr. Chen is an Associate Professor with the Sam and Ann Barshop Institute for Longevity and Aging Studies and the Department of Cell Systems and Anatomy. Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactions Lizhen Chen, Zhao Zhang, Qinyu Han, Barun K. Maity, Leticia Rodrigues, Emily Zboril, Rashmi Adhikari, Su-Hyuk Ko, […]




Congratulations to Bess Frost, PhD on her publication in Trends in Neurosciences!

August 16, 2023

Dr. Frost is an Associate Professor with the Sam and Ann Barshop Institute for Longevity and Aging Studies, the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Disorders, and the Department of Cell Systems and Anatomy.  She is the holder/manager of the Bartell Zachry Distinguished Professor for Research in Neurodegenerative Disorders. Alzheimer’s disease and related tauopathies: […]




UT Health Newsroom: Study links alcohol-associated liver disease to abnormal cutting and rejoining of molecules

July 26, 2023

Original story: UT Health San Antonio Newsroom Splicing deregulation is potential drug target and diagnostic tool Alcohol consumption is a major cause of chronic liver disease. The disease, which has devastating consequences, progresses through stages of hepatitis (inflammation), fibrosis (scarring) and cirrhosis (severe scarring). Advanced disease increases the risk of developing liver cancer, and some […]




Congratulations to Mengwei Zang, MD, PhD and the Zang Lab on their publication in Hepatology!

July 25, 2023

Dr. Zang is a Professor with the Sam and Ann Barshop Institute for Longevity and Aging Studies and the Department of Molecular Medicine.  She is the Ewing Halsell Distinguished Chair in Research and the Associate Director of the MD/PhD Program at UT Health San Antonio. Importantly, this paper has established a fruitful collaboration with esteemed […]