Barshop Institute
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August 28, 2025
Study Highlights Sex-Specific Impact of Keto Diet A recent study from the lab of David Gius, MD, PhD, and published in Cell Reports reveals that a long-term ketogenic diet leads to the accumulation of aging (senescent) cells and oxidative stress—but only in male mice. Female mice did not show these harmful effects. Interestingly, treating male […]
August 27, 2025
Nisi Jiang, PhD, first author and recent Biology of Aging IBMS graduate under the mentorship of James Nelson, PhD, led the first-ever comprehensive review of anti-aging compounds tested by the National Institute on Aging’s Interventions Testing Program. Published in the Journal of Gerontology: Biological Science (July 2025), the landmark study analyzed two decades of data […]
August 25, 2025
Original story: Texas Public Radio By: Bonnie Petrie (August 24, 2025) — A recent review of two decades of research from the National Institute on Aging (NIA) highlighted 13 anti-aging medications that show promise in preclinical studies for significantly extending lifespan. More than that, they seem to improve the quality of those extra years. There’s […]
August 19, 2025
A new study from post-doctoral fellow Kevin Thyne, PhD, shows that methionine restriction, a dietary intervention known to extend lifespan, has different effects on mitochondria and signaling mechanisms that dependent on which tissues are tested, and which sex of mice are tested. Dr. Thyne is a postdoctoral fellow in the lab of Adam Salmon, PhD, […]
August 15, 2025
Highlights: This review explores ferroptosis, an iron-dependent, non-apoptotic form of programmed cell death, as a promising strategy for eliminating senescent cells, which accumulate with age and contribute to tissue dysfunction and age-related diseases such as fibrosis, atherosclerosis, osteoarthritis, and neurodegeneration. The molecular mechanisms of ferroptosis, including iron overload, lipid peroxidation, and oxidative damage, can be […]
August 14, 2025
Study Highlights Skeletal Muscle Changes During Disuse and Rehabilitation A recent study from the lab of Blake Rasmussen, PhD, and published in Physiological Reports examined how short-term skeletal muscle disuse and subsequent rehabilitation affect muscle function and gene expression in healthy middle-aged adults. Participants underwent seven days of unilateral lower-limb suspension followed by a two-week […]
July 29, 2025
Original story: UT Health San Antonio Newsroom Contact: Claire Kowalick, kowalick@uthscsa.edu SAN ANTONIO (July 28, 2025) — Study finds rapamycin shows greatest longevity effect in 20-year NIH Interventions Testing Program The first comprehensive review of two decades of research from the National Institute on Aging’s Interventions Testing Program highlights 13 interventions that show promise in preclinical […]
July 24, 2025
Original story: UT Health San Antonio Newsroom Contact: Claire Kowalick, kowalick@uthscsa.edu SAN ANTONIO (July 22, 2025) — Aging affects all living creatures and is the greatest factor in numerous diseases. The greatest health care burdens are borne by diseases in older patients — a population expected to nearly double by 2050, according to U.S. Census […]
July 22, 2025
Laurence Maeyens, a PhD student in Biology of Aging, won the Poster Pitch Award, along with a cash prize, at the 2025 American Aging Association meeting in Anchorage, Alaska. His winning poster, titled “Timing of castration modulates its life-extending effect in genetically heterogeneous mice: castration at midlife is more effective than at earlier ages”, highlights […]
June 24, 2025
CPRIT awards UT Health San Antonio $3.4 million to increase HPV vaccination rates in Bexar County, develop transformative technologies targeting drug-resistant cancers SAN ANTONIO (June 2, 2025) — The University of Texas Health Science Center at San Antonio (UT Health San Antonio) received $3,395,970 in new academic research and prevention awards as part of […]
